By Pãºblico
Ponce has a large público terminal 787-842-1222 at the intersection of Calle Union and Calle Vives, a few blocks north of Plaza las Delicias. Públicos to San Juan 2 hrs, $20 depart from pier 5A, mostly early in the morning. Call Chóferes Unidos de Ponce at 787-764-0540 to make a reservation; they can also pick you up for a small extra fee. The city has also recently 2012 embarked in an ambituous bus-based mass transit system to aimed at serving the entire city plus parts of the outlying areas.
By car
Ponce is reachable via the main island expressway. It's located about 64 miles from San Juan. The drive takes about 1 hour and 15 minutes. The road highway #52 is modern and convenient and restaurants and shops are readily available throughout the trip.